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The Goldilocks Principle: Optimal Antithrombotic Strategies in the Cardiac ICU

Robert J. DiDomenico, PharmD, FCCP, FHFSA, FACC, Alissa Shega, PharmD, BCCP, and Patrick M. Wieruszewski, PharmD, BCCCP

Robert J. DiDomenico, PharmD, FCCP, FHFSA, FACC
Associate Professor
Assistant Head, Faculty Affairs & Strategic Initiatives
Department of Pharmacy Practice
University of Illinois at Chicago College of Pharmacy
Clinical Pharmacist

UI Health

Alissa Shega, PharmD, BCCP
Clinical Pharmacist – Cardiac Intensive Care Unit
Rush University Medical Center

Patrick M. Wieruszewski, PharmD, BCCCP
Assistant Professor of Anesthesiology
Assistant Professor of Pharmacy
Cardiothoracic Surgery & ECMO Program

Mayo Clinic


Dr. Alissa Shega has no relevant financial conflicts of interest in relation to this activity. Dr. Robert DiDomenico, a speaker, is a consultant for PhaseBio Pharmaceuticals, Inc and received grant/research support from CSL Behring. Dr. Patrick Wieruszewski, a speaker, is a consultant for La Jolla Pharmaceutical Company. All of the relevant financial relationships listed for this individual have been mitigated. The reviewers who contributed to this activity have nothing to disclose.

Type of Activity: Knowledge-based

Learning Objectives:

  • Review the pharmacology of bivalirudin and alternative parenteral anticoagulants used to treat acute coronary syndrome (ACS).
  • Review the safety and efficacy of bivalirudin and other parenteral anticoagulants for the treatment of ACS.
  • Discuss updates in the management of purge solution for patients receiving Impella® support.
  • Discuss pharmacologic strategies for maintenance anticoagulation during extracorporeal membrane oxygenation (ECMO).
Target Audience: Pharmacists Fee: $10 (or $90 for all 10 courses). For C4 2023 participants who registered for the live program, please use the access code provided to you by email.
Release Date: May 16, 2023 Expiration Date: September 25, 2025
Estimated Time to Complete: 1 hour CE: 1.0 contact hours (0.1 CEUs)

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